Detecting non-stationarity of a data-generating process is challenging, particularly when the process is unknown and the only information concerning the process status has to be extracted from a set of observations. This seminar presents a novel approach to change detection that exploits the Intersection of Confidence Intervals (ICI) rule to monitor the process evolution. The proposed change detection test can also identify, after each detection, a set of observation generated by the process in the novel status. These observations are used to reconfigure the test, in order to promptly detect further non-stationarities with respect to the current status. Experimental results show that the proposed test outperforms state-of-the-art solutions, both in terms of efficiency and effectiveness, in particular when a reduced test configuration set is available.